A root and its conjugate always occur with the same multiplicity, because each real quadratic factor (x−z)(x−z) supplies one of each, and every nonreal root comes from such a factor.
multiplicity of 2+i = multiplicity of 2−i
Saying 2+i is double while 2−i is simple breaks that rule, so it cannot happen. The other three are fine: (x2+1)2 has the roots i,−i,i,−i; (x2−6x+10)3 gives 3±i each three times; and (x−5)3 is a legitimate real cubic.