An even power of a real number is never negative, so an even root cannot accept a negative radicand over the reals.
r2≥0 for every real r, so no real r has r2=−4
So −4 is not real (it is the complex number 2i). The other three are fine: 16=4, and the odd roots 3−8=−2 and 5−32=−2 happily take negative radicands.