Factor all four quadratics.
x2+3x−10=(x+5)(x−2),x2+x−6=(x+3)(x−2)
x2−25=(x−5)(x+5),x2−9=(x−3)(x+3)
Flip the divisor and multiply, cancelling x+5, x−2, and x+3.
(x+3)(x−2)(x+5)(x−2)⋅(x−5)(x+5)(x−3)(x+3)=x−5x−3
The restrictions are x=−5, x=−3, x=2, x=3, and x=5.